We're into Week 10 of the 2021 NFL season, and injuries are once again a factor in several key games this coming weekend. Quarterbacks for several teams have their statuses up in the air as of Friday afternoon, and other key players on both sides of the ball do as well.
As teams turn in their final injury reports of the week, let this be your hub for knowing who is in, who is out, and whose status may still be up in their leading up to kickoff. Below, you'll find every injury report and analysis of what it all means for Week 10.
Buffalo Bills (-12.5) at New York Jets
- Bills: LB Tremaine Edmunds (hamstring) OUT; RB Zack Moss (concussion) QUESTIONABLE
- Jets: QB Zach Wilson (knee), T Chuma Edoga (knee) DOUBTFUL; RB Tevin Coleman (hamstring), WR Corey Davis (hip), DL Shaq Lawson (hamstring), OL Alijah Vera-Tucker (toe) QUESTIONABLE
Bills head coach Sean McDermott said cornerback Taron Johnson has cleared concussion protocol, so he'll play Sunday. Moss will have to clear concussion protocol by Saturday in order to play Sunday, or Devin Singletary will get the majority of the carries and be the featured back. McDermott also said that right tackle Spencer Brown and tight end Dawson Knox are "trending in the right direction."
All the players listed as questionable for the Jets were full participants in Friday's practice, so their status for Sunday is looking good. Robert Saleh said he expects all four to play. Coleman hasn't played since Week 6, while Davis hasn't played since Week 8.
Tampa Bay Buccaneers (-9.5) at Washington Football Team
- Buccaneers: WR Antonio Brown (ankle), TE Rob Gronkowski (ribs), CB Rashard Robinson (hamstring) OUT; CB Dee Delaney (ankle), OLB Jason Pierre-Paul (shoulder/hand), WR Chris Godwin (foot) QUESTIONABLE
- Football Team: WR Curtis Samuel (groin), CB Benjamin St-Juste (illness), DE Montez Sweat (jaw) OUT; WR Dyami Brown (knee), T Samuel Cosmi (ankle), TE Sammis Reyes (hip) QUESTIONABLE
Godwin will be a game-time decision, per Buccaneers head coach Bruce Arians. He was a limited participant in Friday's practice. Pierre-Paul didn't practice all week, so the Buccaneers will give him two more days to heal up following the bye week.
All the questionable players for Washington were limited in practice Friday, so their status will come down to Sunday. Samuel and Sweat did not practice all week for the Football Team. Antonio Gibson (hip) was limited all week, but was not given an injury designation.
Jacksonville Jaguars at Indianapolis Colts (-10.5)
- Jaguars: RB James Robinson (heel) QUESTIONABLE
- Colts: CB Xavier Rhodes (calf) OUT; DT DeForest Buckner (back) QUESTIONABLE
Robinson missed last week's victory over the Bills due to the same injury. He was replaced in the lineup by Carlos Hyde, and that would presumably be the case if he were to sit out again.
Buckner didn't practice Friday after being limited Thursday, putting his status up in the air. Colts head coach Frank Reich is optimistic he'll play against Jacksonville, saying his back "locked up" on him during Thursday's practice. T.Y. Hilton is back after clearing concussion protocol and is set to play in his third game of the season.
Detroit Lions at Pittsburgh Steelers (-8)
- Lions: K Austin Seibert (right hip), RB Jamaal Williams (thigh) OUT; T Taylor Decker (finger), OLB Austin Bryant (shoulder) QUESTIONABLE
- Steelers: WR Chase Claypool (toe) OUT
A bye week wasn't enough to get Williams healthy, so the Lions will use D'Andre Swift for the majority of the snaps against Pittsburgh. Jermar Jefferson and Godwin Igwebuike will split duties as the No. 2 back, as Jefferson scored a touchdown in Week 8 against the Eagles. Ryan Santoso will kick for Detroit this week.
The Steelers are relatively healthy heading into this one, with the exception of Claypool -- who injured his toe Monday night against the Bears. With Claypool out, James Washington will get more snaps at wide receiver. Ben Roethlisberger (pectoral and right shoulder) was a full go at practice on Friday and Najee Harris (foot) also was a full participant. Both will play Sunday.
Atlanta Falcons at Dallas Cowboys (-9)
- Falcons: DB Kendall Sheffield (hamstring) OUT; LB Steven Means (knee), TE Lee Smith (back), DL Jonathan Bullard (concussion) DOUBTFUL; DL John Cominsky (shoulder) QUESTIONABLE
- Cowboys: T Tyron Smith (ankle) OUT; WR Cedrick Wilson (shoulder), QB Will Grier (knee) QUESTIONABLE
The Falcons will once again be without wide receiver Calvin Ridley, who is taking a leave of absence to address his mental health.
Dallas will not have Randy Gregory (calf) or Demarcus Lawrence, who are now both on injured reserve after Gregory suffered an injury during practice earlier this week. Expect rookie Micah Parsons to shift back to the edge in Gregory's absence. The Cowboys are expected activate Michael Gallup from injured reserve, as he'll play for the first time since the season opener. Terence Steele is expected to start at left tackle for Smith.
Cleveland Browns at New England Patriots (-2.5)
- Browns: DE Takkarist McKinley (groin) OUT; CB Greedy Williams (groin) QUESTIONABLE
- Patriots: RB Damien Harris (concussion), WR Gunner Olszewski (concussion) OUT; LB Jamie Collins Sr. (ankle) DOUBTFUL; RB Rhamondre Stevenson (concussion), P Jake Bailey (right knee), LB Ja'Whaun Bentley (ribs), K Nick Folk (left knee), WR
N'Keal Harry (knee), LB Dont'a Hightower (ankle), OL Shaq Mason (abdomen), CB Jalen Mills (thigh), TE Jonnu Smith (shoulder), LB Kyle Van Noy (shoulder) QUESTIONABLE
The Browns are going to be without running backs Nick Chubb, Demetric Felton and John Kelly -- all of which were placed on the reserve/COVID-19 list. Baker Mayfield (left shoulder, foot) and and Myles Garrett (foot) were not given an injury designation for Sunday.
The Patriots downgraded both Damien Harris and Gunner Olszewski to out on Saturday. While Stevenson's status is still in question, it's encouraging for his chances to play that he was not dowgraded alongside those two. If he's still ruled out, the club does have Brandon Bolden and J.J. Taylor to deploy out of the backfield. The Patriots can still activate Trent Brown (calf) from injured reserve by Saturday if he can play this week. Brown hasn't played since Week 1.
New Orleans Saints at Tennessee Titans (-3)
- Saints: RB Alvin Kamara (knee), S C.J. Gardner-Johnson, (foot), T Terron Armstead (knee/shoulder) OUT; WR Ty Montgomery (hamstring), DE Carl Granderson (shoulder) QUESTIONABLE
- Titans: S Dane Cruiskshan (knee), LB David Long, (hamstring), CB Greg Mabin (ankle) OUT; LB Rashaan Evans (ankle), DL Teair Tart (groin), WR Julio Jones (Hamstring) QUESTIONABLE
The Saints are going to turn to Mark Ingram to carry the load with Kamara out. Taysom Hill, who is healthy, could also be relied on to carry the running game. P.J. Williams and Bradley Roby are expected to take over the slot with Gardner-Johnson out.
Ryan Tannehill did miss Friday's practice with an illness, but he's expected to play, per Titans head coach Mike Vrabel. A.J. Brown (knee) didn't practice Friday, but wasn't given an injury designation. Jones missed part of Friday's practice so he'll be a game-time decision.
Minnesota Vikings at Los Angeles Chargers (-3)
- Vikings: LB Anthony Barr (knee), DL Michael Pierce (elbow) OUT; DB Bashaud Breeland (groin) QUESTIONABLE
- Chargers: CB Ryan Smith (knee) OUT; CB Michael Davis (hamstring), RB Justin Jackson (quad) DOUBTFUL; S Nasir Adderley (ankle), WR Keenan Allen (knee), OLB Joey Bosa (ankle), DB Mark Webb Jr. (knee) QUESTIONABLE
Minnesota will be without at least two valuable defensive pieces, while a third is listed as questionable. Against a Chargers offense that appeared to get back on track last week, that's not a great situation to be in.
Bosa not practicing Friday after being limited Thursday is a big setback for the Chargers. But he is expected to play, per Chargers head coach Brandon Staley. Allen was limited Friday, but he's also expected to play.
Carolina Panthers at Arizona Cardinals (-10.5)
- Panthers: DB Rashaan Melvin (hand), DB Stantley Thomas-Oliver III (toe) OUT; DE Brian Burns (foot), LB Frankie Luvu (knee) QUESTIONABLE
- Cardinals: RB Chase Edmonds (ankle), OL Justin Pugh (calf), RB Jonathan Ward (concussion), S James Wiggins (knee), QB Kyler Murray (ankle), WR DeAndre Hopkins(hamstring) OUT; S Budda Baker (concussion/knee), OL Max Garcia (Achilles), WR Rondale Moore (neck/concussion), DE Jordan Phillips (groin) QUESTIONABLE
- Cam Newton will suit up for the Panthers, but with Burns being upgraded to a full participant in practice on Friday, it seems like things are looking up for him.
The Cardinals have already announced that Murray and Hopkins will be out for Sunday's game. Colt McCoy will get the start again for Arizona while A.J. Green, Rondale Moore, and Christian Kirk will get more snaps with Hopkins sidelined. Sean Harlow is expected to start at left guard.
Philadelphia Eagles at Denver Broncos (-2.5)
- Eagles: T Andre Dillard (knee) DE Josh Sweat (concussion)
- Broncos: T Garett Bolles (ankle), T Bobby Massie (ankle) OUT; TE Albert Okwuegbunam (knee), WR Tim Patrick (knee), OLB Malik Reed (hip), S Caden Sterns (shoulder), CB Patrick Surtain II (knee), G Dalton Risner (foot), RB Mike Boone (hip), LB Baron Browning (back) QUESTIONABLE
Eagles head coach Nick Sirianni didn't seem concerned about Sweat, who is in the concussion protocol until Saturday. The Eagles should have Dillard available as well.
The Broncos already have two starting offensive linemen out for Sunday's game and a slew of injuries to deal with. Patrick and Surtain were limited Friday, as was Risner. Calvin Anderson is expected to start for Bolles at left tackle while Cameron Fleming is expected to start for Massie. The Broncos will have backup quarterback Drew Lock out due to COVID-19, as with offensive coordinator Pat Shurmur.
Seattle Seahawks at Green Bay Packers (-3.5)
- Seahawks: S Marquise Blair (knee), CB Bless Austin (personal), LB Cody Barton (quad) OUT; DT Al Woods (non-injury related) QUESTIONABLE
- Packers: T David Bakhtiari (knee), TE Dominique Dafney (hamstring), DL Kingsley Keke (concussion) DOUBTFUL; DL Kenny Clark (back), WR Equanimeous St. Brown (ankle), CB Eric Stokes (knee) QUESTIONABLE
Quarterback Russell Wilson and wide receiver Dee Eskridge are both back from injured reserve, so they'll play Sunday. Woods will make the trip, even though he was listed as questionable. Blair is out for the season.
Bakhtiari was back on the practice field this week after starting the year on the PUP list, but he didn't practice Friday. His return may have to wait another week. Clark was limited in Friday's practice, and is expected to be a game-time decision this week.
Kansas City Chiefs (-2.5) at Las Vegas Raiders
- Chiefs: OL Lucas Niang (ribs), T Mike Remmers (knee) OUT; CB L'Jarius Sneed (ankle/wrist) QUESTIONABLE
- Raiders: S Tyree Gillespie (hamstring), LB Nick Kwiatkoski (ankle) OUT; CB Keisean Nixon (ankle), CB Amik Robertson (hip) DOUBTFUL
The Chiefs are going to be down both their right tackles Sunday, so Andrew Wylie is in line to start. Running back Clyde Edwards-Helaire is still on injured reserve, and isn't expected to be activated in time for Sunday.
None of the Raiders that were given injury designations are starters. K.J. Wright was the only one in doubt, and he was a full participant in Friday's practice and wasn't given an injury designation.
Los Angeles Rams (-3.5) at San Francisco 49ers (MNF)
Reports to come.