Injuries are a mainstay in the NFL. And Week 13 is no exception. So, which banged-up players have a chance of suiting up for this weekend's action? We've got you covered below with a full rundown of Wednesday practice reports for every game on tap.
All NFL odds courtesy of William Hill Sportsbook.
Wednesday practice reports
Browns at Titans (-5.5)
For the Browns, cornerback Denzel Ward was the only player who did not practice on Wednesday due to a calf injury. Running back Kareem Hunt (thigh) and offensive tackle Jack Conklin (knee) were limited participants.
The Titans were missing several notable names at practice on Wednesday, as cornerback Adoree' Jackson (knee), offensive guard Rodger Saffold (ankle), defensive lineman Jeffery Simmons (knee) and tight end Jonnu Smith (knee) were out.
Saints (-3) at Falcons
Saints stars Alvin Kamara (foot) and Michael Thomas (ankle) were limited participants in practice on Wednesday, while cornerback Janoris Jenkins (knee), wide receiver Marquez Callaway (knee) and offensive weapon Deonte Harris (neck) were held out.
Star wide receiver Julio Jones (hamstring) was limited at Falcons practice, meaning he may or may not be available for Atlanta come Sunday. Ditto for running back Todd Gurley (knee).
Colts (-3) at Texans
The Colts had a host of players sit out of practice on Wednesday. Among them were left tackle Anthony Castonzo (knee), quarterback Philip Rivers (toe), linebacker Bobby Okereke (ankle) and safety Khari Willis (back/quad).
Texans cornerback Lonnie Johnson was a limited participant with a knee injury, as was punter Bryan Anger due to an injured right quad.
Raiders (-8) at Jets
Several big names missed practice for the Raiders on Wednesday. Among them were safety Johnathan Abram (knee), wide receiver Nelson Agholor (ankle), cornerback Damon Arnette (concussion/neck), defensive tackle Maliek Collins (hamstring/ankle) and last but certainly not least, running back Josh Jacobs (ankle).
Only two Jets missed practice on Wednesday due to injury: linebacker Blake Cashman (hamstring) and offensive tackle George Fant (knee/ankle). Quarterback Sam Darnold was a full participant with his right shoulder injury, while wide receiver Breshad Perriman was limited with a shoulder injury.
Bengals at Dolphins (-11.5)
Bengals offensive guard Alex Lewis sat out on Wednesday due to his concussion, while safety Brandon Wilson was out with a hamstring issue.
Miami is reportedly optimistic that quarterback Tua Tagovailoa (thumb) will be fully healthy for Sunday's game, thus enabling the rookie to reclaim the starting job from Ryan Fitzpatrick. He was a limited participant in practice on Wednesday along with running back Salvon Ahmed, who is dealing with a shoulder injury.
Lions at Bears (-3)
Surprise, surprise: Wide receiver Kenny Golladay (hip) did not practice for Detroit, which suggests the Lions will once again be without their top pass target. Joining him on the sideline was cornerback Jeff Okudah (shoulder) and defensive lineman Da'Shawn Hand (groin). Quarterback Matthew Stafford was also limited with a right thumb injury.
While quarterback Nick Foles was a limited participant in practice on Wednesday, Matt Nagy has already ruled him out for Week 13. That means Mitchell Trubisky will again be the starting quarterback. Star linebacker Khalil Mack (back) missed practice, as did offensive tackle Charles Leno Jr. (toe) and defensive tackle Akiem Hicks (hamstring).
Vikings (-10) at Jaguars
Tight end Irv Smith Jr. sat out on Wednesday due to a back injury while running back Dalvin Cook and offensive lineman Ezra Cleveland were limited participants due to ankle injuries. Center Brett Jones was also limited due to a neck injury.
Coach Doug Marrone said Gardner Minshew (thumb) is "fine" after several weeks on the sidelines but still named Mike Glennon, Week 12's starter, as the No. 1 quarterback for Sunday's matchup with Minnesota.
Giants at Seahawks (-10)
Quarterback Daniel Jones sat out of practice on Wednesday due to his hamstring injury, and his status for Sunday is certainly already in question. Wide receivers Sterling Shepard (toe/shoulder) and Darius Slayton (shoulder/foot) were limited participants.
For the Seahawks, offensive tackle Brandon Shell (ankle), running back Travis Homer (wrist/thumb/knee), cornerback Tre Flowers (hamstring) and defensive end Carlos Dunlap (foot) missed practice on Wednesday. Running backs Chris Carson (foot) and Carlos Hyde (toe) were limited participants.
Rams (-3) at Cardinals
Rams linebacker Terrell Lewis sat out of practice on Wednesday with a knee injury, while offense lineman Brian Allen was able to participate in a limited fashion with his knee issue.
For the Cardinals, offensive lineman Justin Pugh (ankle), safety Jalen Thompson (ankle) and safety Charles Washington (groin) sat out of practice on Wednesday. More importantly, quarterback Kyler Murray was limited with a right shoulder injury.
Patriots at Chargers (PK)
Several Patriots were limited participants in practice on Wednesday, such as quarterback Cam Newton (abdomen), kicker Nick Folk (back) and defensive back J.C. Jackson (hip). The only player who missed practice, however, was linebacker Anfernee Jennings due to an illness.
Defensive end Joey Bosa (shin), cornerback Chris Harris (foot), cornerback Casey Hayward Jr. (groin), linebacker Denzel Perryman (back) and rookie wideout Joe Reed (ribs) missed practice on Wednesday, while running back Kalen Ballage (ankle), offensive guard Trai Turner (ankle) and offensive tackle Bryan Bulaga (illness) were limited.
Eagles at Packers (-8.5)
Fletcher Cox sat out with a neck injury, as did safety Rudy Ford with a hamstring issue. Tight end Zach Ertz was limited with an ankle injury.
Several notable Packers players were limited in practice on Wednesday. Among them were wide receiver Allen Lazard (core), tight end Marcedes Lewis (knee), safety Darnell Savage (back), punter JK Scott (right quad) and wide receiver Equanimeous St. Brown (knee).
Broncos at Chiefs (-14.5)
Running back Phillip Lindsay (knee) was a no-go at Broncos practice -- a bad sign for his availability against Kansas City, with Melvin Gordon likely to remain atop the backfield depth chart. Rookie wide receiver Jerry Jeudy was a limited participant with an ankle injury.
Chiefs cornerback Bashaud Breeland missed practice with an illness while defensive end Tanoh Kpassagnon was limited with a hip issue.