Offensive Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Quarterback | T. LawrenceTrevor Lawrence | C. BeathardC.J. Beathard | |
| Running Back | T. EtienneTravis Etienne | J. HastyJaMycal Hasty | |
| Wide Receiver | C. KirkChristian Kirk | Z. JonesZay Jones | |
| Tight End | E. EngramEvan Engram | C. ManhertzChris Manhertz | |
| Left Tackle | W. LittleWalker Little | — | — |
| Left Guard | T. ShatleyTyler Shatley | B. HanceBlake Hance | — |
| Center | L. FortnerLuke Fortner | — | — |
| Right Guard | B. ScherffBrandon Scherff | C. Van LanenCole Van Lanen | — |
| Right Tackle | J. TaylorJawaan Taylor | — | — |
Defensive Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Left Defensive End | F. FatukasiFoley Fatukasi | A. KeyArden Key | |
| Nose Tackle | D. HamiltonDaVon Hamilton | C. PetersCorey Peters | |
| Right Defensive End | R. Robertson-HarrisRoy Robertson-Harris | A. GotsisAdam Gotsis | |
| Left Inside Linebacker | C. MumaChad Muma | C. JohnsonCaleb Johnson | — |
| Right Inside Linebacker | F. OluokunFoye Oluokun | D. LloydDevin Lloyd | — |
| Strongside Linebacker | T. WalkerTravon Walker | K. ChaissonK'Lavon Chaisson | |
| Weakside Linebacker | J. AllenJosh Allen | D. DixonDe'Shaan Dixon | |
| Right Cornerback | M. BrownMontaric Brown | C. ClaybrooksChris Claybrooks | |
| Left Cornerback | T. CampbellTyson Campbell | D. WilliamsDarious Williams | |
| Strong Safety | R. JenkinsRayshawn Jenkins | A. WingardAndrew Wingard | |
| Free Safety | A. CiscoAndre Cisco | D. ThomasDaniel Thomas | — |
Special Teams Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Punter | L. CookeLogan Cooke | — | — |
| Kicker | R. PattersonRiley Patterson | J. McCourtJames McCourt | — |
| Long Snapper | R. MatiscikRoss Matiscik | — | — |
| Holder | L. CookeLogan Cooke | — | — |
| Punt Returner | J. AgnewJamal Agnew | C. KirkChristian Kirk | |
| Kick Returner | J. AgnewJamal Agnew | J. HastyJaMycal Hasty |