Offensive Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Quarterback | J. HurtsJalen Hurts | T. McKeeTanner McKee | |
| Running Back | S. BarkleySaquon Barkley | — | |
| Wide Receiver | A. BrownA.J. Brown | D. SmithDeVonta Smith | |
| Tight End | D. GoedertDallas Goedert | G. CalcaterraGrant Calcaterra | |
| Left Tackle | J. MailataJordan Mailata | T. SteenTyler Steen | |
| Center | C. JurgensCam Jurgens | B. TothBrett Toth | — |
| Right Tackle | L. JohnsonLane Johnson | D. KinnardDarian Kinnard | — |
Defensive Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Left Defensive End | M. OjomoMoro Ojomo | — | — |
| Nose Tackle | J. DavisJordan Davis | B. YoungByron Young | — |
| Right Defensive End | J. CarterJalen Carter | T. BookerThomas Booker | |
| Left Inside Linebacker | Z. BaunZack Baun | J. Trotter Jr.Jeremiah Trotter Jr. | |
| Right Inside Linebacker | N. DeanNakobe Dean | D. GantDallas Gant | — |
| Strongside Linebacker | B. HuffBryce Huff | O. MathisOchaun Mathis | — |
| Weakside Linebacker | N. SmithNolan Smith | — | |
| Right Cornerback | K. RingoKelee Ringo | — | — |
| Left Cornerback | Q. MitchellQuinyon Mitchell | E. RicksEli Ricks | |
| Slot Cornerback | C. DeJeanCooper DeJean | — | |
| Strong Safety | — | T. McCollumTristin McCollum | |
| Free Safety | R. BlankenshipReed Blankenship | — | — |
Special Teams Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Punter | B. MannBraden Mann | — | — |
| Kicker | J. ElliottJake Elliott | — | — |
| Long Snapper | C. HughlettCharley Hughlett | — | — |
| Holder | B. MannBraden Mann | — | — |
| Punt Returner | C. DeJeanCooper DeJean | — | — |
| Kick Returner | — | W. ShipleyWill Shipley | — |