From game-time decisions to injuries so significant they affect the value of every single position, let's break down the Fantasy and DFS impact of injuries for every Week 13 matchup. Know when to pivot and how your fantasy roster will be affected.

Below, you'll find a game-by-game look at the injuries you need to know that will have the biggest impact for Fantasy leagues, as well as the implications for DFS players. This week's list of notable names includes quarterbacks Justin Fields and Matthew Stafford; running backs Leonard Fournette, Travis Etienne, J.K. Dobbins and Najee Harris; receivers Mike Williams and Ja'Marr Chase; tight ends Logan Thomas and David Njoku; and many others, including key offensive line and defensive injuries to know.

10.0-7.00
6.99 - 5.01
5.00 - 0
Start 'em
Sit 'em
Sun, Dec 4 at 1:00 pm ET •
ATL +1, O/U 42

Notable injuries

Steelers

  • RB Najee Harris (oblique) - Cleared
  • RB Jaylen Warren (hamstring) - Questionable
  • RB Benny Snell (knee) - Cleared
  • C Mason Cole (foot) - Cleared
  • DT Larry Ogunjobi (toe) - Cleared
  • OLB T.J. Watt (ribs) - Questionable
  • ILB Myles Jack (knee) - Cleared
  • CB Ahkello Witherspoon (hamstring) - Out

Falcons

  • RB Damien Williams (ribs) - TBD
  • OT Chuma Edoga (knee) - Questionable
  • DT Jalen Dalton (toe) - Questionable
  • LB Arnold Ebiketie (forearm) - Questionable

Despite missing practice Wednesday and Thursday and logging a limited practice on Friday, Najee Harris is cleared for Week 13. Jaylen Warren is still listed as questionable. However, he logged three full practices this week and seems on track to play. Benny Snell is still listed as questionable but if both Harris and Warren are active, Snell would likely have little involvement, and the backfield would likely be split between Harris and Warren. It's difficult for either back to have upside in a split backfield but the matchup against Atlanta is excellent. Atlanta has allowed the ninth-most Fantasy points to opposing running backs. Harris is an RB2 and Warren has flex appeal with his pass-catching upside.  

While the Falcons have no new significant injuries, Kyle Pitts is officially out for the remainder of the season. MyCole Pruitt stepped up as the most productive tight end in his absence but is not a reliable start. Olamide Zaccheaus saw a significant increase in work last week with five receptions on eight targets for 91 yards. He's a low-end flex option in deep leagues, with defenses focused on shutting down Drake London. 

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DFS impact

If both Harris and Warren are active, neither has enough upside for DFS lineups. Monitor reports throughout the weekend for details regarding snap counts and limitations to see if either back is a viable option. 

10.0-7.00
6.99 - 5.01
5.00 - 0
Start 'em
Sit 'em
Sun, Dec 4 at 1:00 pm ET •
BAL -8, O/U 38.5

Notable injuries

Broncos

  • RB Mike Boone (ankle) - TBD
  • FB Andrew Beck (hamstring) - Out
  • WR Jerry Jeudy (ankle) - Questionable
  • WR K.J. Hamler (hamstring) - Out
  • WR Courtland Sutton (illness) - Questionable
  • OG Dalton Risner (shoulder) - Cleared
  • DE Dre'Mont Jones (illness) - Cleared
  • CB K'Waun Williams (knee) - Questionable

Ravens

  • QB Lamar Jackson (quad) - Cleared
  • RB J.K. Dobbins (knee) - TBD
  • WR Tylan Wallace (hamstring) - Out
  • TE Isaiah Likely (ankle) - Cleared
  • OT Ronnie Stanley (ankle) - Questionable
  • S Kyle Hamilton (knee) - Questionable
  • CB Marlon Humphrey (ankle) - Questionable

Jerry Jeudy is questionable and logged a limited practice on Friday. While he's trending in the right direction, Fantasy managers need to monitor his status throughout the weekend. Courtland Sutton was added to the injury report on Friday with an illness and is questionable as well. Baltimore is a good matchup for receivers but it's difficult to trust any Broncos given their offensive struggles. When both receivers have been healthy in the past, Jeudy has been the more productive option. Jeudy is a flex option if active and not limited. Sutton is a risky start if Jeudy is active and a flex option if Jeudy is inactive.

J.K. Dobbins is unlikely to return this week, leaving Gus Edwards as the top option in Baltimore. Edwards returned from injury in Week 12 as the clear lead back with 16 carries for 52 yards and a touchdown. The matchup against Denver is difficult and Edwards lacks pass catching upside, making Edwards an RB3/flex option this week.

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DFS impact

This is a difficult game to utilize any options in DFS because of low-upside. If Jeudy is out, Kendall Hinton is a low-priced option but his upside is very limited. With the offensive struggles, he has a ceiling of 10 Fantasy points.  

10.0-7.00
6.99 - 5.01
5.00 - 0
Start 'em
Sit 'em
Sun, Dec 4 at 1:00 pm ET •
CHI +4.5, O/U 43.5

Notable injuries

Packers

  • QB Aaron Rodgers (ribs) - Cleared
  • RB Aaron Jones (shin) - Cleared
  • RB A.J. Dillon (quadriceps) - Cleared
  • WR Romeo Doubs (ankle) - Questionable
  • OT David Bakhtiari (knee) - Out
  • OL Elgton Jenkins (knee) - Cleared
  • ILB De'Vondre Campbell (knee) - Questionable
  • FS Darnell Savage (foot) - Doubtful

Bears

  • QB Justin Fields (shoulder) - Cleared
  • QB Trevor Siemian (oblique) - Out
  • WR Darnell Mooney (ankle) - IR
  • WR Dante Pettis (illness) - Cleared
  • OT Riley Reiff (back) - Questionable
  • OT Larry Borom (ankle, knee) - Out
  • FS Eddie Jackson (foot) - IR
  • SS Jaquan Brisker (concussion) - Out
  • CB Kyler Gordon (knee) - Out
  • CB Kindle Vildor (ankle) - Questionable

The big news here is that Aaron Rodgers was cleared to play. Rodgers may lack upside but has a solid floor and given the matchup with a struggling Chicago defense, Rodgers does have a high ceiling. Despite Rodgers' struggles and ongoing injuries, he's managed to feed receivers and Christian Watson is a low-end WR2 and high-end flex option. Allen Lazard is a flex option and Randall Cobb is a low-end flex option in deep leagues if Romeo Doubs remains sidelined.

For Chicago, Justin Fields is cleared and will play in Week 13. The Packers are a better matchup on the ground but Fields is still a strong QB1 option. The Bears will be without Darnell Mooney, who suffered a season-ending injury. His absence increases value for Chase Claypool as a flex option and Cole Kmet as a low-end TE1.

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DFS impact

While this game is difficult to target and stack as a whole -- as both teams struggle on the ground, which could limit pass volume -- there are several well-priced value plays. Claypool is now the WR1 for Chicago, priced at just $3,800 on DraftKings. Kmet is also $3,800 and could be the safety option for Fields with Mooney inactive. Christian Watson is a mere $5,200 and Cobb is $4,200.  

10.0-7.00
6.99 - 5.01
5.00 - 0
Start 'em
Sit 'em
Sun, Dec 4 at 1:00 pm ET •
DET +1, O/U 51.5

Notable injuries

Jaguars

  • WR Zay Jones (chest) - Questionable
  • RB Travis Etienne (foot) - Questionable
  • FS Andre Cisco (shoulder) - Questionable

Lions

  • WR Quintez Cephus (foot) - TBD
  • WR Jameson Williams (knee) - TBD
  • C Frank Ragnow (foot) - Cleared
  • OG Evan Brown (ankle) - Out
  • OG Jonah Jackson (concussion) - Cleared
  • OT Penei Sewell (ankle) - Cleared
  • DE Josh Paschal (knee) - Cleared
  • CB Jeff Okudah (concussion) - Cleared

Jacksonville's key injured players are still listed as questionable so Fantasy managers will need to monitor their status throughout the weekend. However, Etienne announced he intends to play. If Etienne is active, he is the only viable running back for Jacksonville. While JaMycal Hasty performed well in his absence, Etienne is the clear RB1 in a fantastic matchup with Detroit. He has top-10 upside if active. 

For Detroit, the majority of players are cleared for Week 13 with the exception of players set to return from IR. It's unclear if Jameson Williams will make his debut this week.

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DFS impact  

Zay Jones is priced up slightly after his recent success but is still a huge bargain at $4,900 on DraftKings, given the matchup. If active, Jones is an excellent value play. Etienne is priced at his typical level with a solid DFS option if he's active. While Jameson Williams is very cost-effective, avoid using him if active.

10.0-7.00
6.99 - 5.01
5.00 - 0
Start 'em
Sit 'em
Sun, Dec 4 at 1:00 pm ET •
HOU +7, O/U 47

Notable injuries

Browns

  • TE David Njoku (knee) - Out
  • DE Myles Garrett (shoulder) - Cleared
  • CB Greg Newsome (concussion) - Cleared
  • CB Denzel Ward (ankle) - Cleared

Texans

  • WR Brandin Cooks (calf) - Out
  • RB Rex Burkhead (concussion) - Questionable
  • OG Kenyon Green (illness) - Cleared
  • OLB Christian Harris (shoulder) - Cleared
  • CB Derek Stingley Jr. (hamstring) - Out

Friday's practice report took a significant turn for both teams. David Njoku, Brandin Cooks and Derek Stingley Jr. are all out for Week 13. When Njoku is healthy, he's commanded a solid amount of targets. His absence in the return of Deshaun Watson should narrow the target distribution and increase value for Amari Cooper and Donovan Peoples-Jones, particularly with Stingley out. Fantasy managers in very deep leagues can take a shot at David Bell, whose targets are recently increase over the past three weeks.

For the Texans, Nico Collins has lead the team in targets recently and the absence of Cooks should continue to open up opportunities. The Texans offense is struggling, but volume should be there enough to support Collins as a low-end flex option.

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DFS impact

While Collins is just a low-end flex option in season long leagues, he has excellent appeal in DFS with Cooks out. Collins is just $4,200 on DraftKings and is a solid stand-alone option and a key bring-back option in any lineups involvement Watson. Without Njoku, Cooper and Peoples-Jones are interesting options for Cleveland. While risky with the unknown of how Watson will perform in his first game back, they have high upside suitable for large tournament play.

10.0-7.00
6.99 - 5.01
5.00 - 0
Start 'em
Sit 'em
Sun, Dec 4 at 1:00 pm ET •
MIN -3, O/U 44.5

Notable injuries

Jets

  • RB Michael Carter (ankle) - Doubtful
  • OT Duane Brown (shoulder) - Questionable
  • OT Cedric Ogbuehi (groin, illness) - Doubtful
  • S Ashtyn Davis (hamstring) - Out

Vikings

  • OT Christian Darrisaw (concussion) - Out
  • CB Andrew Booth Jr. (knee) - IR
  • CB Akayleb Evans (concussion) - Cleared

While teams like Jacksonville and Pittsburgh await clarity at running back, the Jets are planning for the absence of Michael Carter, who is doubtful for Week 13. The most likely candidate to step up is Zonovan Knight, who is coming off a strong performance of 14 carries for 69 yards and three receptions for 34 yards. James Robinson was a healthy scratch in Week 12 and Fantasy managers should monitor his status on Sunday. If all three are active, this is a backfield to avoid in a what is typically a tough defensive matchup for running backs.

While the Vikings' Fantasy contributors are active, the absence of Christian Darrisaw is significant for Fantasy purposes. The Jets are a strong defensive matchup and without Darrisaw, Cousins could be at risk for increased pressure. Cook could also struggle on the ground. Fantasy managers should avoid Cousins if possible. While Cook is still a solid start, lower expectations.

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DFS impact

With the absence of Darrisaw, avoid Cook and Cousins in DFS lineups. Justin Jefferson is still a fine option. For the Jets, we need clarity on the availability of James Robinson. If Robinson is inactive again, Knight is a bargain at just $4,600 and does have the upside needed for tournament play with the potential of receiving work.  

10.0-7.00
6.99 - 5.01
5.00 - 0
Start 'em
Sit 'em
Sun, Dec 4 at 1:00 pm ET •
NYG +2.5, O/U 40.5

Notable injuries

Commanders

  • QB Carson Wentz (finger) - TBD
  • RB Antonio Gibson (foot) - Questionable
  • TE Logan Thomas (ribs) - Cleared
  • C Tyler Larsen (shoulder) - Cleared
  • OG Trai Turner (knee) - Out
  • DE Chase Young (knee) - Questionable
  • CB Benjamin St-Juste (ankle) - Out

Giants

  • WR Darius Slayton (illness) - Questionable
  • WR Richie James (knee) - Questionable
  • TE Daniel Bellinger (eye) - Questionable
  • C Jon Feliciano (neck) - Questionable
  • OG Shane Lemieux (toe) - Out
  • DE Leonard Williams (neck) - Cleared
  • FS Xavier McKinney (hand) - Out
  • CB Darnay Holmes (shoulder) - Questionable
  • CB Adoree' Jackson (knee) - Out
  • CB Fabian Moreau (oblique) - Questionable

The only area to monitor for Washington is the availability of Gibson, who is trending in the right direction after missing practice earlier in the week. If he's active, both Gibson and Brian Robinson are low-end RB2s. But if Gibson is inactive, Robinson has RB1 upside with J.D. McKissic already sidelined. A potential Gibson absence could benefit Curtis Samuel but it's too risky to utilize him outside of very deep leagues.

For the Giants, Slayton and James are questionable and there is no pivot option if they are inactive. But the most significant players to note are on defense, where the injuries continue to pile up for the Giants and increase appeal for Washington offensive players.

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DFS impact

Robinson is reasonably-priced at just $5,300 on DraftKings. If Gibson is out, Robinson is a solid play in cash lineups. Avoid Giants receivers as a whole if Slayton and James are out. The only viable option would be Saquon Barkley as the Giants would lean aggressively on the run.  

10.0-7.00
6.99 - 5.01
5.00 - 0
Start 'em
Sit 'em
Sun, Dec 4 at 1:00 pm ET •
PHI -5, O/U 44.5

Notable injuries

Titans

  • RB Hassan Haskins (hip) - Questionable
  • WR Treylon Burks (illness) - Cleared
  • C Ben Jones (concussion) - Cleared
  • OG Nate Davis (knee) - Cleared
  • DE Jeffery Simmons (ankle) - Questionable
  • DE Denico Autry (knee) - Out
  • CB Elijah Molden (groin) - Out
  • K Randy Bullock (calf) - Cleared

Eagles

  • WR DeVonta Smith (knee) - Cleared
  • WR Zach Pascal (groin) - Cleared
  • DE Robert Quinn (knee) - Out
  • FS Chauncey Gardner-Johnson (abdomen) - Out

The Titans and Eagles offenses are healthy but both teams have injuries on defense that could increase upside for pass catchers on both sides. Burks, Smith and A.J. Brown are all viable options this week.

DFS impact

There's no significant DFS impact in this matchup from injuries with healthy offensive players.  

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10.0-7.00
6.99 - 5.01
5.00 - 0
Start 'em
Sit 'em
Sun, Dec 4 at 4:05 pm ET •
LAR +7.5, O/U 41.5

Notable injuries

Seahawks

  • WR D'Wayne Eskridge (hand) - IR
  • WR Marquise Goodwin (illness) - Cleared
  • RB Travis Homer (illness) - Questionable
  • OG Damien Lewis (illness) - Cleared
  • OT Abraham Lucas (knee) - Cleared
  • ILB Jordyn Brooks (illness) - Cleared

Rams

  • QB Matthew Stafford (neck) - Out
  • RB Cam Akers (illness) - Cleared
  • WR Allen Robinson (foot) - IR
  • WR Lance McCutcheon (shoulder) - Out
  • C Brian Allen (thumb) - Questionable
  • OT Ty Nsekhe (ankle) - Cleared
  • OG Oday Aboushi (illness) - Cleared
  • DE A'Shawn Robinson (knee) - IR
  • DE Aaron Donald (ankle) - Out
  • LB Terrell Lewis (back) - Out
  • OLB Ernest Jones (back) - Questionable
  • CB Troy Hill (groin) - Questionable

The big news in this matchup is focused around the Rams. Stafford is out, Robinson is on IR and the Rams are already without Cooper Kupp. Multiple defensive players are out, including Aaron Donald. Rams receiving options should be avoided as a whole. Kyren Williams has appeal with the potential to see an uptick in targets as the pass catching back. Williams has low-end flex value. 

DFS impact

While Williams does have some deep league appeal in season-long leagues, he is too risky in DFS. The injuries for the Rams defensively could open up opportunities for the Seahawks. But if the game gets out of hand, upside could be limited.  

10.0-7.00
6.99 - 5.01
5.00 - 0
Start 'em
Sit 'em
Sun, Dec 4 at 4:05 pm ET •
SF -4, O/U 46.5

Notable injuries

Dolphins

  • QB Teddy Bridgewater (knee) - Questionable
  • RB Raheem Mostert (knee) - Cleared
  • RB Myles Gaskin (shoulder) - Questionable
  • OT Terron Armstead (pectoral) - Doubtful
  • OT Austin Jackson (ankle) - Out

49ers

  • QB Jimmy Garoppolo (knee) - Cleared
  • RB Christian McCaffrey (knee) - Cleared
  • RB Elijah Mitchell (knee) - Out
  • WR Deebo Samuel (hamstring) - Questionable
  • OT Trent Williams (back) - Questionable
  • OG Spencer Burford (ankle) - Questionable
  • DT Arik Armstead (foot) - Cleared

In the biggest revenge game of the week, the majority of key offensive players are cleared. Deebo Samuel is the one question mark in this game. Fantasy managers should monitor his status through the weekend because, if active, Samuel could be in line for increased usage on the ground with Elijah Mitchell out for the year. Samuel has offered limited upside on the ground but the 49ers want to limit and monitor usage for McCaffrey which could benefit Samuel's Fantasy production.

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DFS impact

The primary DFS impact in this game is around who to avoid. The Dolphins will likely be without Terron Armstead, which could affect the Dolphins run game against a strong 49ers defense, and Raheem Mostert is set to return this week. The Dolphins backfield is still viable in season-long leagues but should be avoided in DFS.

10.0-7.00
6.99 - 5.01
5.00 - 0
Start 'em
Sit 'em
Sun, Dec 4 at 4:25 pm ET •
CIN +2, O/U 52.5

Notable injuries

Chiefs

  • WR Kadarius Toney (hamstring) - Out
  • RB Jerick McKinnon (hamstring) - Cleared

Bengals

  • RB Joe Mixon (concussion) - Questionable
  • WR Ja'Marr Chase (hip) - Questionable
  • DT D.J. Reader (ankle) - Cleared
  • LB Logan Wilson (illness) - Questionable

Kadarius Toney is out again and Cincinnati is a tough defensive matchup. But in the absence of Toney and Mecole Hardman, Skyy Moore has increased his snap count and target share. Moore has low-end flex value, particularly in PPR formats.

Mixon is trending in the right direction but still remains in concussion protocol. Fantasy managers must monitor his status throughout the weekend, as he is a must-start is active. If Mixon is inactive, Samaje Perine remains a solid RB2 with RB1 upside. Chase should also be monitored through the weekend. If active, Chase should start in all formats.

DFS impact

For those willing to get risky in tournament play, Chase could be an interesting option if DFS players are unwilling to pay the price without clarity around his status and potential limitations. Skyy Moore is a great value play as well in tournament play at just $3,100.

10.0-7.00
6.99 - 5.01
5.00 - 0
Start 'em
Sit 'em
Sun, Dec 4 at 4:25 pm ET •
LV +1.5, O/U 50.5

Notable injuries

Chargers

  • WR Mike Williams (ankle) - Out
  • C Corey Linsley (concussion) - Out
  • OT Trey Pipkins (knee) - Out
  • LB Drue Tranquill (illness) - Questionable
  • S Nasir Adderley (thumb) - Questionable

Raiders

  • RB Josh Jacobs (calf) - Questionable
  • RB Brandon Bolden (calf) - Questionable
  • DT Andrew Billings (lower leg) - Questionable
  • MLB Denzel Perryman (wrist) - Questionable

Mike Williams is out again, making Josh Palmer a solid WR2 option given the matchup. The Raiders have struggled immensely and Palmer has a safe floor and high ceiling. DeAndre Carter is a low-end flex option as well. Despite the absence of Williams, Justin Herbert remains a QB1.

Fantasy managers must monitor Jacobs' status throughout the weekend. Jacobs is coming off one of the most impressive performances of any offensive player this season and played through this injury in Week 12. If Jacobs is active, he has continued top-three upside.

DFS impact

There are value plays from injuries in this game with Palmer, Carter and potentially Ameer Abdullah. Abdullah is priced at just $4,600 on DraftKings and has pass-catching upside ideal for GPP if Jacobs is out. Palmer is priced up at $5,600 but still a bargain with the matchup. The deep value play is Carter at $3,900. While target share is inconsistent for Carter, he's had two touchdowns in the past three games so he has an ideal ceiling in DFS.  

10.0-7.00
6.99 - 5.01
5.00 - 0
Start 'em
Sit 'em
Sun, Dec 4 at 8:20 pm ET •
DAL -11, O/U 43.5

Notable injuries

Colts

  • TE Jelani Woods (quadriceps) - Questionable
  • OT Braden Smith (illness) - Out
  • CB Kenny Moore (shin) - Out
  • CB Isaiah Rodgers (ankle) - Questionable

Cowboys

  • WR Michael Gallup (illness) - Questionable
  • WR James Washington (foot) - TBD
  • DE DeMarcus Lawrence (foot) - Cleared
  • OLB Anthony Barr (hamstring) - Questionable
  • SS Jayron Kearse (shoulder) - Questionable
  • CB Trevon Diggs (illness) - Questionable

There are no significant offensive injuries for either team in this matchup. Jelani Woods is coming off a breakout performance but given the matchup, it's difficult to trust him in season-long leagues.

The Cowboys' defensive injuries are something to monitor. If Diggs, Kearse and Barr can't play, that would open things up significantly for Fantasy managers to feel more comfortable with Michael Pittman Jr. as a WR2 and Parris Campbell as a flex option.

DFS impact

If Dallas is missing multiple key plays on defense, Campbell has strong appeal as a value play.  

10.0-7.00
6.99 - 5.01
5.00 - 0
Start 'em
Sit 'em
Mon, Dec 5 at 8:15 pm ET •
TB -3.5, O/U 40.5

Notable injuries

Saints

  • RB Mark Ingram (knee) - TBD
  • WR Jarvis Landry (ankle) - TBD
  • WR Rashid Shaheed (back) - TBD
  • WR Kevin White (illness) - TBD
  • TE Juwan Johnson (ankle) - TBD
  • C Josh Andrews (ankle) - TBD
  • LB Pete Werner (ankle) - TBD
  • CB Marshon Lattimore (abdomen) - TBD

Buccaneers

  • RB Leonard Fournette (hip) - TBD
  • WR Russell Gage (hamstring) - TBD
  • TE Cameron Brate (illness) - TBD
  • OG Luke Goedeke (foot) - TBD
  • OT Tristan Wirfs (ankle) - Out
  • NT Vita Vea (foot) - TBD
  • CB Sean Murphy-Bunting (quadriceps) - TBD
  • DB Logan Ryan (foot) - TBD
  • FS Mike Edwards (hamstring) - TBD
  • SS Antoine Winfield Jr. (ankle) - TBD

The Saints have a continuously long list of injuries but the significant ones to monitor are Jarvis Landry, who has deep league appeal, and Juwan Johnson, who has strong touchdown equity with five total scores over the past six weeks. Johnson is coming off a game of zero receptions on two targets in a tough defensive draw. Tampa is another tough matchup but tight end is a difficult position and Johnson does have TE1 upside. One significant defensive injury Fantasy managers must monitor is Marshon Lattimore. Mike Evans has struggled against Lattimore throughout his career and if Lattimore is active, Evans is a risky play.

For the Bucs, Leonard Fournette logged two full practices this week and is likely to return on Monday. The backfield should be split between Fournette and Rachaad White, who was trending towards a 50/50 split with Fournette prior to the injury. White has been the more productive back recently and it's possible both backs are RB2 options this week.

DFS impact

The potential return of Fournette makes it difficult to play either Fournette or White in showdown matchups. Lean towards the pass catching options depending on the news with New Orleans defensive injuries.