Regular season

Date OPP Result Record
Nov 9, 2021 vs
SIUE
W 88-77
 1-0
Nov 12, 2021 vs
New Hamp.
W 75-70
 2-0
Nov 15, 2021 vs
10
Illinois
W 67-66
 3-0
Nov 18, 2021 @
Ole Miss
W 78-72
 4-0
Nov 19, 2021 @
West Virginia
W 82-71
 5-0
Nov 21, 2021 vs
22
St. Bona.
L 70-54
 5-1
Nov 27, 2021 vs
N. Illinois
W 80-66
 6-1
Nov 30, 2021 vs
Jackson St.
W 83-54
 7-1
Dec 4, 2021 @
23
Wisconsin
L 89-76
 7-2
Dec 8, 2021 @
Kansas St.
W 64-63
 8-2
Dec 11, 2021 vs
4
UCLA
L 67-56
 8-3
Dec 18, 2021 @
22
Xavier
L 80-71
 8-4
Dec 21, 2021 vs
UConn
L 78-70
 8-5
Dec 29, 2021 @
St. John's
Postponed
—
Jan 1, 2022 vs
Creighton
L 75-69 / 2OT
 8-6
Jan 4, 2022 vs
16
Providence
W 88-56
 9-6
Jan 7, 2022 @
Georgetown
W 92-64
 10-6
Jan 11, 2022 vs
DePaul
W 87-76
 11-6
Jan 15, 2022 vs
20
Seton Hall
W 73-72
 12-6
Jan 19, 2022 @
11
Villanova
W 57-54
 13-6
Jan 23, 2022 vs
20
Xavier
W 75-64
 14-6
Jan 26, 2022 @
Seton Hall
W 73-63
 15-6
Jan 30, 2022 @
17
Providence
L 65-63
 15-7
Feb 2, 2022 vs
12
Villanova
W 83-73
 16-7
Feb 8, 2022 @
24
UConn
L 80-72
 16-8
Feb 12, 2022 @
Butler
L 85-79
 16-9
Feb 16, 2022 vs
Georgetown
W 77-66
 17-9
Feb 20, 2022 @
Creighton
L 83-82
 17-10
Feb 26, 2022 vs
Butler
W 64-56
 18-10
Mar 2, 2022 @
DePaul
L 91-80
 18-11
Mar 5, 2022 vs
St. John's
W 85-77
 19-11

Postseason

Date OPP Result Record
Mar 10, 2022 @
4
Creighton
L 74-63
 19-12
Mar 17, 2022 @
8
N. Carolina
L 95-63
 19-13