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After opening the season with losses, the Indiana State Sycamores and Indiana Hoosiers will look to turn things around on Friday night when they battle in an intrastate matchup in Bloomington, Ind. Indiana State kicked off the 2023 season on Aug. 31 with a 27-0 home loss to Eastern Illinois. Indiana, meanwhile, dropped a 23-3 decision to third-ranked Ohio State this past Saturday. The Sycamores finished 10th in the Missouri Valley Football Conference at 1-7 and 2-9 overall in 2022, while the Hoosiers were sixth in the Big Ten East Division at 2-7 and were 4-8 overall.

The game from Memorial Stadium is set to kick off at 7 p.m. ET. Indiana State's defense allowed 397.1 yards per game last year, while Indiana's allowed 450.3. The Hoosiers are favored by 30.5 points in the latest Indiana State vs. Indiana odds, while the over/under for total points scored is 45.5. Before making any Indiana vs. Indiana State picks, be sure to see the college football predictions from SportsLine expert Micah Roberts

Roberts has worked in the Las Vegas sportsbook industry for more than 20 years, including a 13-year run as Station Casinos' book director. He's on a 6-0 run on college football picks involving the Hoosiers, returning $600 for $100 bettors. Anyone who has followed him is way up.

Now, Roberts has set his sights on Indiana vs. Indiana State and just locked in its picks and CFB predictions. You can head to SportsLine now to see Roberts' picks. Here are several college football odds and betting lines for Indiana State vs. Indiana:

  • Indiana vs. Indiana State spread: Indiana -30.5
  • Indiana vs. Indiana State over/under: 45.5 points
  • ISU: The Sycamores were just 2-9 overall in 2022 at the FCS level
  • IND: The Hoosiers have hit the first-half under total in four of their last five home games
  • Indiana vs. Indiana State picks: See picks at SportsLine

Why Indiana can cover

Junior wide receiver Donaven McCulley looks to step in and play a bigger role with the receiving corps this season. In the opening-game loss to Ohio State, McCulley caught one pass for six yards. He is in his second year with the program. In 2022, he finished with 16 receptions for 169 yards (10.6 average) and one touchdown. His lone score came in a 56-14 loss at No. 2 Ohio State on Nov. 12.

On defense, senior linebacker Aaron Casey is back and is ready to help set the tone. In last week's loss to the Buckeyes, he led the team with 11 tackles, including nine solo. He led the Hoosiers in stops a year ago with 85, including 48 solo, to go along with 1.5 sacks for 11 yards. He forced two fumbles and broke up two passes. In four-plus seasons at Indiana, Casey has compiled 141 tackles, including 84 solo, with 3.5 sacks, two pass breakups and two forced fumbles. See who to back at SportsLine

Why Indiana State can cover

Wide receiver Dakota Caton helps lead the Sycamores' offense. In the season opener against Eastern Illinois, he caught a team-high six passes for 70 yards (11.7 average), including a long of 32 yards. The senior is in his fourth season with the team, and has been a consistent contributor every year. Last season, he caught 23 passes for 291 yards (12.7 average) and two touchdowns, including a long reception of 53 yards. For his career, he has 69 receptions for 809 yards (11.7 average) and six TDs.

Also boosting the wide receiving corps is senior wide receiver Harry Van Dyne. After beginning his career at Minnesota, he has played the last three seasons at Indiana State. In 2022, he had a career-high 24 receptions for 284 yards (11.8 average) and two touchdowns. In last week's loss to Eastern Illinois, he caught three passes for 25 yards (8.3 average), including a long of 11 yards. See who to back at SportsLine

How to make Indiana State vs. Indiana picks

Roberts has analyzed this matchup from every angle. He has discovered a critical X-factor that has him jumping all over one pick. He's only sharing what it is at SportsLine.

What is the best bet for Indiana vs. Indiana State? Visit SportsLine now to see the top Indiana State vs. Indiana pick, all from the expert who is 6-0 on his last six picks involving the Hoosiers, and find out.