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USATSI

After there were just three games on Monday, the Tuesday MLB schedule is packed with 15 games. The action begins with three games at 6:40 p.m. ET and concludes with Dodgers vs. Diamondbacks getting underway at 10:10 p.m. ET. In some of the more intriguing matchups, the latest MLB odds list the Cubs as slight -126 favorites (risk $126 to win $100) against the Phillies, the Royals at -116 against the Rays and the Braves (-186) against the Giants.

Should you play the money line on those favorites, or are there better MLB lines to target on this full slate? Before making any MLB picks or parlays, be sure to check out the MLB predictions and betting advice from SportsLine's proven simulation model.

The SportsLine Projection Model simulates every MLB game 10,000 times. It entered Week 15 of the 2024 MLB season a profitable 44-34 on all-top rated MLB picks this season. Dating back to last season, it is on a 22-8 roll on top-rated run-line picks (+935). Anybody following has seen strong returns.

For Tuesday, the model has locked in four confident MLB best bets for games that begin at 6:40 p.m. ET or later. If you successfully parlay the picks, you'd be looking at a payout of more than 6-1. You can see the model's MLB picks only at SportsLine. 

Top MLB picks today

After simulating every game on Tuesday 10,000 times, the model is picking the Twins (-110) to beat the Tigers in a 7:40 p.m. ET matchup at Target Field. The Twins have clearly been the better team this season, but the Tigers are getting a decent amount of credit from oddsmakers because Tarik Skubal is on the hill. Skubal is 9-3 with a 2.32 ERA on the season.

However, Skubal hasn't been as good on the road recently, giving up four earned runs in his past two road outings. Minnesota, meanwhile, has Simeon Woods Richardson on the mound. He's 3-1 with a 3.41 ERA. Detroit's offense is struggling and SportsLine's model projects that the Tigers failed to get to four runs in the simulations. The Twins win outright more than 60% of the time, making them the clear value pick as small favorites. See the model's top MLB picks here.

How to make Tuesday MLB parlays

The model also locked in two other best bets for Tuesday, including backing an underdog to win outright well over 50% of the time. You can see the model's MLB Tuesday best bets and parlay only at SportsLine.

What MLB picks should you target for a payout of more than +600? Visit SportsLine now to see the MLB best bets for Tuesday from the model that's on a 22-8 run on top-rated MLB run-line picks, and find out.