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The Mississippi State Bulldogs will take on the No. 14 Ole Miss Rebels in the 2022 Egg Bowl on Thursday. It is the 31st meeting between the programs on Thanksgiving, with Ole Miss winning the last two meetings. The Rebels are 8-3 overall and 4-3 in the SEC despite back-to-back losses to Alabama and Arkansas. Mississippi State is coming off a 56-7 win over East Tennessee State, improving to 7-4 overall this season.

Caesars Sportsbook lists the Rebels as 2-point home favorites in Oxford for this 7 p.m. ET kickoff. The total number of points Vegas thinks will be scored, or the over/under, is 63 in the latest Mississippi State vs. Ole Miss odds. Before locking in any Ole Miss vs. Mississippi State picks, you need to see the college football predictions and betting advice from SportsLine's advanced computer model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Mississippi State vs. Ole Miss and just locked in its 2022 Egg Bowl picks and predictions. You can head to SportsLine now to see the model's picks. Here are several college football odds and betting lines for Ole Miss vs. Mississippi State:

  • Mississippi State vs. Ole Miss spread: Ole Miss -2
  • Mississippi State vs. Ole Miss over/under: 63 points 
  • Mississippi State vs. Ole Miss money line: Ole Miss -130, Miss State +110
  • MSU: The Bulldogs are 5-5-1 against the spread this season 
  • MISS: The Rebels are 4-6-1 against the spread this season 
  • Mississippi State vs. Ole Miss picks: See picks here
Featured Game | Ole Miss Rebels vs. Mississippi State Bulldogs

Why Mississippi State can cover

Veteran quarterback Will Rogers leads an effective passing offense for the Bulldogs. Mississippi State is No. 2 in the SEC with 321.2 passing yards per game, and the Bulldogs are completing 67.6% of pass attempts overall. Rogers leads the conference with 3,474 passing yards individually, and he is averaging 388 passing yards with four touchdowns and no interceptions in two career games against Ole Miss. 

Mississippi State has the second-most touchdown passes (33) in the SEC, with only six interceptions and 33.5 points per game this season. On defense, the Bulldogs are above-average in the SEC in points allowed (24.4 per game), total yards allowed (351.7 per game), passing yards allowed (202.2 per game), completion rate allowed (56.9%), and yards per pass attempt allowed (6.4). Mississippi State also has more interceptions (14) than touchdown passes allowed (13) this season.

Why Ole Miss can cover

The Rebels have obscenely impressive offensive numbers and high-end skill position talent. Ole Miss ranks in the top five nationally in total yards per game (505.5) and rushing yards per game (278.3) this season, and the Rebels are averaging 5.8 yards per carry with 31 rushing touchdowns. The ground game leads Ole Miss to more than 35 points per game and a 50.3% third down efficiency rate, with Quinshon Judkins at the center of the attack. 

He leads the SEC with 1,385 rushing yards, and Judkins has 16 rushing touchdowns to go along with 6.0 yards per carry. Zach Evans adds 899 yards on only 131 carries this season, and quarterback Jaxson Dart is a dual threat with 552 rushing yards and 5.2 yards per carry. Dart also adds 2,363 passing yards and 8.4 yards per pass attempt, and Ole Miss has two of the top four wide receivers in the SEC this season, with both Jonathan Mingo and Malik Heath both exceeding 750 rushing yards in 11 games.

How to make Mississippi State vs. Ole Miss picks

SportsLine's model is leaning Under on the total, projecting 57 combined points. The model also says one side of the spread hits in over 60% of simulations. You can only see the model's 2022 Egg Bowl picks at SportsLine.

So who wins Mississippi State vs. Ole Miss? And which side of the spread hits in over 60% of simulations? Visit SportsLine now to see which side of the Mississippi State vs. Ole Miss spread you need to jump on Thursday, all from the model that has crushed its college football picks, and find out.