The South Carolina Gamecocks will face off against the Notre Dame Fighting Irish at 7 p.m. ET on Tuesday at Colonial Life Arena as part of the 2023 ACC/SEC Challenge. South Carolina is 5-0 overall and 2-0 at home. Notre Dame is 3-2 overall and hasn't played on the road yet. South Carolina is 4-1 ATS this season, while Notre Dame has a 2-3 ATS mark.

The Gamecocks are favored by 7.5 points in the latest South Carolina vs. Notre Dame odds via SportsLine consensus, and the over/under is set at 133 points. Before entering any Notre Dame vs. South Carolina picks, you'll want to see the college basketball predictions from the model at SportsLine.

The model simulates every Division I college basketball game 10,000 times. It enters Week 4 of the 2023-24 season on an 94-61 roll on all top-rated college basketball picks dating back to last season, returning more than $1,800 for $100 players. It is also off to an 8-2 roll on top-rated spread picks this season. Anyone following has seen huge returns.

The model has set its sights on Notre Dame vs. South Carolina. You can head to SportsLine to see its picks. Here are several college basketball betting lines for the game:

  • South Carolina vs. Notre Dame spread: South Carolina -7.5
  • South Carolina vs. Notre Dame over/under: 133 points
  • South Carolina vs. Notre Dame money line: South Carolina -343, Notre Dame +267
  • South Carolina vs. Notre Dame picks: See picks here

What you need to know about South Carolina

South Carolina put another mark in the win column last Sunday to keep its perfect season alive. The Gamecocks walked away with a 75-68 victory over Grand Canyon. South Carolina can attribute much of its success in that matchup to B.J. Mack, who scored 27 points. Another player making a difference was Jacobi Wright, who scored 10 points.

Mack leads the team in scoring with 16 points per game. Meechie Johnson (14.4 ppg), Myles Stute (12 ppg) and Wright (9.2 ppg) have also been big factors on offense. The Gamecocks are averaging 76.6 points and 15.2 assists per game, giving them an edge over Notre Dame in both those categories. 

What you need to know about Notre Dame

Meanwhile, the Fighting Irish made easy work of Maryland-Eastern Shore on Wednesday in a 75-55 victory. The win made it back-to-back victories for Notre Dame, who lost the prior two games against Auburn and Western Carolina

Notre Dame got its win over Maryland-Eastern Shore thanks to several key players, but it was freshman Braeden Shrewsberry out in front with 13 points. Markus Burton (18 ppg) has been the only consistent source of offense for the Irish this season, though they have been solid defensively, giving up just 67.2 points per game. 

How to make South Carolina vs. Notre Dame picks

The model has simulated South Carolina vs. Notre Dame 10,000 times and the results are in. The model is leaning Over, and it's also generated a point-spread pick that is hitting in over 60% of simulations. You can only see the pick at SportsLine.

Who wins Notre Dame vs. South Carolina, and which side of the spread hits in over 60% of simulations? Visit SportsLine to fine out, all from the model that's on a 94-61 roll on top-rated college basketball picks