A UFC lightweight champion will be crowned at UFC 280. Charles Oliveira vs. Islam Makhachev headlines a stacked pay-per-view on Saturday in Abu Dhabi. The card also features UFC bantamweight champion Aljamain Sterling vs. former titleholder TJ Dillashaw.

Oliveira was forced to vacate the UFC lightweight title in May over a controversial and confusing weight miss, yet punched a ticket back to his unclaimed crown with a first-round finish of Justin Gaethje. Makhachev -- the pupil and spiritual successor of undefeated former champion Khabib Nurmagomedov -- has mauled his way to a world title shot after a nearly spotless 12-year run in MMA.

Elsewhere, Yan is also back in action when he takes on rising contender Sean O'Malley. "Suga" is looking to enter the title picture against his toughest competition to date. Another bout between potential contenders is also on the main card when Matuesz Gamrot takes on Beneil Dariush at lightweight. Plus, welterweight contenders Belal Muhammad and Sean Brady are set to throw down in the featured prelim bout with plenty at stake.

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Below is all the information you need to catch UFC 280 on Saturday night. 

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How to watch UFC 280 prelims

Date: Oct. 22  | Location: Etihad Arena -- Yas Island, Abu Dhabi
Time: 10:30 a.m. ET for early prelims
Channel: ESPNNews | Stream: fuboTV (Try for free)

How to watch UFC 280 main card

Date: Oct. 22  | Location: Etihad Arena -- Yas Island, Abu Dhabi
Time: 2 p.m. ET
Stream: ESPN+ PPV | Price: $74.99

Now, here's a look at the UFC 280 main fight card and betting odds via Caesars Sportsbook.

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UFC 280 main card, odds

FavoriteUnderdogWeightclass
Islam Makhachev -190Charles Oliveira +160Vacant lightweight title
Aljamain Sterling (c) -175TJ Dillashaw +150Bantamweight title
Petr Yan -270Sean O'Malley +220Bantamweights
Matuesz Gamrot -190Beneil Dariush +160Lightweights
Manon Fiorot -210Katlyn Chookagian +175Women's flyweights

Who wins Oliveira vs. Makhachev? And how exactly does each fight end? Visit SportsLine now to get detailed picks on every fight at UFC 280, all from the incomparable expert who's up more than $13,000 on MMA in the past three-plus years, and find out.