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No. 7 Penn State will host No. 24 Iowa on Saturday in the latest edition of the Big Ten on CBS, and Nittany Lions officials are calling on their fans to white out Beaver Stadium for this primetime college football matchup. Both teams are 3-0 on the season with Penn State beating West Virginia and Delaware before kicking off the Big Ten season with a win over Illinois last week. Meanwhile, Iowa has beaten Utah State, Iowa State and Western Michigan. Penn State is 3-0 against the spread on the season while Iowa is 2-1 against the number.

Kickoff is scheduled for 7:30 p.m. ET on Saturday in State College, Penn. The Nittany Lions are 14-point favorites at home while the over/under is 38.5 in the latest Penn State vs. Iowa odds from the SportsLine consensus. Before making any Iowa vs. Penn State picks, you need to see the college football predictions and betting advice from the SportsLine Projection Model.

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The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, it has generated a stunning profit of nearly $2,500 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now the model has dialed in on Penn State vs. Iowa and just revealed its coveted picks and predictions. You can head to SportsLine now to see the model's Iowa vs. Penn State picks. Now, here are the college football odds and trends for Iowa vs. Penn State: 

  • Penn State vs. Iowa spread: Penn State -14
  • Penn State vs. Iowa over/under: 38.5 points 
  • Penn State vs. Iowa money line: Penn State -671, Iowa +466
  • Penn State vs. Iowa picks: See picks here
  • Penn State vs. Iowa streaming: Paramount+

Why Penn State can cover

James Franklin is now in his 10th season in State College and is coming off his fourth career 11-win season since taking over and a Rose Bowl win over Utah. Franklin has turned the offense over to sophomore quarterback Drew Allar this season and he's completing 67% of his passes for 8.4 yards per attempt without an interception.

Meanwhile, the Penn State defense ranks 13th in the nation in scoring defense (11.7 ppg) and is only allowing 267.3 yards of total offense per game. Sophomore linebacker Abdul Carter had 10.5 TFL, 6.5 sacks and two forced fumbles last year as a freshman and he has a sack and an interception already this season. See Week 4 college football picks at SportsLine

Why Iowa can cover

The Hawkeyes are still working through some offensive issues after ranking 123rd in the nation in scoring last season but Iowa has averaged a more respectable 28.3 points per game so far in 2023. Michigan transfer Cade McNamara now runs the offense and while it hasn't been the smoothest transition, he has had multiple passing touchdowns in two of three games.

However, the Iowa defense has once again been stellar, allowing only 12.3 points and 286.0 yards of total offense per game. Fourth-year linebacker Jay Higgins has 32 total tackles with three pass deflections and a forced fumble in three games. The team as a whole has also been incredibly disciplined, only drawing one penalty for five yards in the last two games. See Penn State vs. Iowa picks at SportsLine

How to make Iowa vs. Penn State picks

SportsLine's model is leaning Over on the total, projecting 40 combined points. It also says one side of the spread hits more than 50% of the time. You can see the model's pick at SportsLine

So who wins Penn State vs. Iowa, and which side of the spread hits more than 50% of the time? Visit SportsLine now to see which side of the spread to jump on, all from the advanced model that is up almost $2,500 on top-rated spread picks since its inception, and find out, and don't forget to stream on Paramount+.