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Teams looking for their first Conference USA win meet up in a midweek spot as the FIU Panthers travel to take on New Mexico State on Wednesday night. FIU is 3-2 overall and 0-2 in the conference, while New Mexico State is 2-3 overall with a loss to Liberty in its only conference matchup. FIU beat New Mexico State 21-7 in 2022, but this is the first matchup of the schools as Conference USA foes after New Mexico State officially joined on July 1 of this year. 

Kickoff is set for 9 p.m. ET on CBS Sports Network. The Aggies are 6.5-point favorites in the SportsLine consensus FIU vs. New Mexico State odds, while the over/under for total points is 48.5. Before locking in any New Mexico State vs. FIU picks, you need to see the college football predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, the proprietary computer model has generated a stunning profit of more than $2,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed the model has seen huge returns.

Now, the model has set its sights on FIU vs. New Mexico State and just revealed its picks and predictions. You can visit SportsLine now to see the model's CFB picks. Here are several college football odds and trends for New Mexico State vs. FIU:

  • FIU vs. New Mexico State spread: Aggies -6.5
  • FIU vs. New Mexico State over/under: 48.5 points
  • FIU vs. New Mexico State money line: Aggies -245, Panthers +199
  • NMSU: 3-2 ATS this season in all games 
  • FIU: 3-1 ATS this season as an underdog 
  • FIU vs. New Mexico State picks: See picks at SportsLine
  • FIU vs. New Mexico State live stream: fubo (try for free)

Why New Mexico State can cover

The Aggies rank third in Conference USA in scoring offense (29.8 ppg) and they have an impressive group of pass catchers. Sophomore receiver Jonathan Brady utilizes his deep speed and strong hands to challenge defenses vertically. The Nevada native is leading the team in receiving yards (252) and receiving touchdowns (3) and is averaging 25.2 yards per reception. In Week 4 versus New Mexico, Brady finished three catches with 109 yards and two scores.

Junior receiver Trent Hudson brings tremendous size and physicality that is especially useful in the red zone. Hudson (6-foot-3) easily wins contested passes and provides the offense with a big target. The Texas native has reeled eight passes for 143 yards and three touchdowns. Junior running back Star Thomas is a reliable receiving threat out of the backfield. Thomas has snagged 11 receptions with 113 yards. See which team to pick here.

Why FIU can cover

The Panthers ran into a buzzsaw against Liberty last time out, but they'd been playing well before that. FIU had won three straight and covered in three of the previous four. Two of those wins came as outright underdogs as well, so they shouldn't be overlooked in this spot. 

Quarterback Keyone Jenkins has thrown for 1,000 yards and five touchdowns, while adding two scores on the ground. Receiver Kris Mitchell (23-459-4) is one of the best at his position in the conference and running back Shomari Lawrence (53-312-2) has impressed as well. FIU's defense has given up a lot of yardage but ranks fourth in the conference in scoring defense at 25.6 points, so backers will hope it bends but doesn't break against a talented NMSU offense.  See which time to pick here.

How to make FIU vs. New Mexico State picks

SportsLine's model is leaning Over on the point total, projecting 56 combined points. The model also says one side of the spread is the better value. You can see the model's picks at SportsLine

So who wins New Mexico State vs. FIU, and which side of the spread is the better value? Visit SportsLine now to see which side of the spread you need to jump on, all from the model that has notched a profit of more than $2,000 on its top-rated college football spread picks, and find out.