We've got another exciting American Athletic matchup on the schedule as the South Florida Bulls and the SMU Mustangs are set to tip at 12 p.m. ET on Sunday at the Yuengling Center. South Florida is 20-5 overall and 13-2 at home, while SMU is 19-8 overall and 5-5 on the road. The Mustangs have won six of the last 10 meetings against the Bulls.  

This time around, SMU is favored by 2.5 points in the latest South Florida vs. SMU odds, and the over/under is 147 points. Before entering any South Florida vs. SMU picks, you'll want to see the NCAA Basketball predictions from the proven computer model at SportsLine.

The model simulates every Division I college basketball game 10,000 times. It enters Week 16 of the 2023-24 season on a 136-89 roll on all top-rated college basketball picks dating back to last season, returning nearly $2,500 for $100 players. It is also off to a sizzling 25-13 start on top-rated spread picks this season. Anyone following has seen huge returns.

The model has set its sights on SMU vs. South Florida. You can head to SportsLine to see its picks. Here are several college basketball betting lines for the game:

  • South Florida vs. SMU spread: USF +2.5
  • South Florida vs. SMU over/under: 147 points
  • South Florida vs. SMU money line: South Florida: +122, SMU: -145
  • South Florida vs. SMU picks: See picks here

What you need to know about South Florida

South Florida entered its tilt with the UTSA Roadrunners with 11 consecutive wins but the Bulls will enter their next game with 12. The Bulls came out on top against the Roadrunners by a score of 66-61 on Wednesday. South Florida's success was the result of a balanced attack that saw several players step up, but Kasean Pryor led the charge by dropping a double-double with 12 points and 10 rebounds. 

The Bulls are led offensively by guard Chris Youngblood, who's scoring 15.0 points per game. Youngblood's effectiveness on the offensive end of the floor is a big reason why South Florida has won 11 consecutive games at home.

What you need to know about SMU

Meanwhile, SMU unfortunately witnessed the end of its six-game winning streak on Thursday. The Mustangs took an 80-70 hit to the loss column at the hands of the FAU Owls. SMU found out winning isn't easy when you don't work as a unit and post 13 fewer assists than your opponent.

Despite the defeat, SMU saw several players rise to the challenge and make noteworthy plays. Keon Ambrose-Hylton, who scored 11 points along with five rebounds, was perhaps the best of all. However, the Mustangs struggled to work together and finished the game with only five assists. That's the fewest assists they've managed all season.

How to make South Florida vs. SMU picks

The model has simulated South Florida vs. SMU 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that hits in well over 50% of simulations. You can only see the pick at SportsLine.

So who wins SMU vs. South Florida, and which side of the spread hits well over 50% of the time? Visit SportsLine now to find out which side of the spread you need to jump on, all from the model that is on a 136-89 roll on its top-ranked college basketball picks, and find out.