Players who have combined to reach 41 Grand Slam finals clash when second-ranked Novak Djokovic meets third-ranked Daniil Medvedev at the 2023 U.S. Open final on Sunday at 4 p.m. ET at Arthur Ashe Stadium in Flushing Meadows, N.Y. This is the third meeting between the two this year. Djokovic posted a 6-3, 6-4 win in the semifinals at Adelaide in January, while Medvedev earned a 6-4, 6-4 semifinal victory at Dubai in March. The pair have met 14 times in their careers, with Djokovic holding a 9-5 edge.

Djokovic is listed as the -250 favorite on the money line, while Medvedev is at +190. Djokovic is looking to win his third Grand Slam of the year after reaching the final in all four events in 2023. The only loss so far came against Carlos Alcaraz 1-6, 7-6 (8), 6-1, 3-6, 6-4 at Wimbledon. Before making any Djokovic vs. Medvedev picks or 2023 U.S. Open predictions, you need to see what tennis expert Jose Onorato has to say.

Onorato grew up playing competitive tennis in Caracas, Venezuela. After coming to the U.S., he trained with famed coach Nick Bollettieri at IMG Academy in Florida and faced players like Robert Farah, now one of the world's top-ranked doubles players. Onorato, who holds dual degrees in finance and economics from the University of Miami, does extensive research before placing any tennis bet. 

He studies current form, players' tendencies on a particular surface, weather conditions and many other relevant factors. That systematic approach has helped Onorato go 128-90-7 (+69.25 units) since 2022.

Now, Onorato has scrutinized the latest U.S. Open 2023 odds and released his coveted best bet for the Djokovic vs. Medvedev final match. He's sharing his pick and analysis only at SportsLine.

Novak Djokovic vs. Daniil Medvedev preview

Onorato sees both players as being capable of getting the win. The 36-year-old Djokovic is showing no signs of slowing down. In fact, with a win, he will be averaging two Grand Slam victories a year since 2018. Djokovic won both the 2023 Australian Open and French Open, and was the runner-up at Wimbledon. For his career, he has 23 Grand Slam titles and 12 runner-up finishes.

Djokovic advanced to the U.S. Open final with a 6-3, 6-2, 7-6 (4) win over American Ben Shelton in the semifinals. It was the fifth straight-set win of the tournament for him. Djokovic has been dominant on hard surfaces, and has lost just six times on the surface in his last 79 matches, including a 26-1 mark this year. Overall, he is 44-5 (89.7%) in 2023.

The 27-year-old Medvedev has also had his way on the court this year. He has posted a 55-11 record (83.3%), including five tournament titles. He has also reached the finals once, the semifinals three times and the quarterfinals three times. Medvedev advanced to the final by knocking off top-ranked Carlos Alcaraz 7-6 (3), 6-1, 3-6, 6-3 in the semifinals.

Since turning pro in 2014, Medvedev has had a lot of success. He has earned 20 singles titles, and has reached a Grand Slam final for the fifth time, winning the U.S. Open two years ago. For his career, he has compiled a 479-191 (71.5%) overall record, including 214-67 (76.2%) on hard surfaces. His career mark at New York is 29-5 (85.3%). See who Onorato is backing right here.

How to make Medvedev vs. Djokovic picks

In addition to a full breakdown of the match, Onorato has revealed his best bet. Be sure to see Onorato's pick and analysis before locking in your 2023 U.S. Open picks for Djokovic vs. Medvedev.

Who wins Djokovic vs. Medvedev in the finals of the 2023 U.S. Open? Visit SportsLine now to see Jose Onorato's best bet for the men's singles final, all from the tennis expert who's up nearly 70 units since 2022, and find out.