The No. 16 LSU Tigers (2-1) will aim for their third consecutive victory when they host the UCLA Bruins (1-1) on Saturday afternoon. LSU lost to then-No. 23 USC in its season opener, but it responded with wins over Nicholls State and South Carolina. UCLA is trying to bounce back from a 42-13 loss to Indiana at home last week. This is the second game of a home-and-home series that began with a 38-27 UCLA victory in 2021.
Kickoff is set for 3:30 p.m. ET on Saturday at Tiger Stadium. LSU is favored by 22.5 points in the latest LSU vs. UCLA odds, while the over/under is 56 points, per SportsLine consensus. Before entering any UCLA vs. LSU picks, you'll want to see the college football predictions from the model at SportsLine.
The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a profit of over $2,000 for $100 players on its top-rated college football picks against the spread. It is also coming off a profitable 13-9 season on top-rated spread picks and is off to a 5-2 start on over/under picks this season. Anyone who has followed it has seen strong returns.
The model has set its sights on UCLA-LSU. You can head to SportsLine to see its picks. Here are several college football betting lines for the game:
- LSU vs. UCLA spread: LSU -22.5
- LSU vs. UCLA over/under: 56 points
- LSU vs. UCLA money line: LSU -2222, UCLA: +1046
- LSU vs. UCLA picks: See picks here
Why LSU can cover
LSU has responded nicely to its season-opening loss to USC, starting with a 44-21 win over Nicholls State two weeks ago. The Tigers added a 36-33 win at South Carolina last week, erasing a 17-0 deficit. Junior quarterback Garrett Nussmeier completed 24 of 40 passes for 285 yards and two touchdowns after racking up 302 yards and six touchdowns against Nicholls.
Freshman running back Caden Durham burst onto the scene with 11 carries for 98 yards and two touchdowns in the comeback win over the Gamecocks. UCLA has been disappointing in each of its first two games, failing to cover as a 13.5-point favorite against Hawaii before getting crushed by Indiana as a 4-point underdog. LSU is riding an 11-game home winning streak, while UCLA has only covered the spread twice in its last eight games. See which team to pick here.
Why UCLA can cover
UCLA had its Big Ten debut spoiled by Indiana last week, but the Bruins will be motivated to bounce back against a ranked opponent this week. Senior quarterback Ethan Garbers has thrown for 409 yards and a touchdown through his first two games of the season after completing 67.1% of his passes with 11 touchdowns last year. Garbers has also rushed for 68 yards, giving UCLA a dual-threat weapon.
LSU has not covered the spread in any of its first three games, yet this line has jumped a full touchdown since the opener. The Tigers have failed to cover the spread in five consecutive September games and are 3-9 against the spread in their last 12 games in Week 4. Bettors have had success fading LSU lately, and they are laying a huge number this week. See which team to pick here.
How to make LSU vs. UCLA picks
The model has simulated UCLA vs. LSU 10,000 times and the results are in. The model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 70% of simulations. You can only see the pick at SportsLine.
So who wins LSU vs. UCLA, and which side of the spread is hitting well over 70% of the time? Visit SportsLine now to see which side of the UCLA vs. LSU spread to jump on, all from the advanced computer model that's up over $2,000 on its top-rated college football spread picks since its inception, and find out.