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The Arizona Wildcats look to win their first Territorial Cup matchup since 2016 as they host the Arizona State Sun Devils on Friday afternoon. Arizona enters at 4-7 off a 31-20 home loss to Washington State, while Arizona State, 3-8, fell in their home finale to No. 21 Oregon State, 31-7. The Sun Devils have won five straight in the rivalry, including a 38-15 win over the Wildcats last season. Arizona is 5-5 against the spread, while Arizona State is 3-7 ATS in 2022.

Kickoff is scheduled for 3 p.m. ET at Arizona Stadium. The Wildcats are favored by 4 points in the latest Arizona vs. Arizona State odds from Caesars Sportsbook, and the over/under is set at 65.5. Before entering any Arizona State vs. Arizona picks, you'll want to see the college football predictions and betting advice from the model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Arizona vs. Arizona State and just locked in its picks and CFB predictions. You can head to SportsLine now to see the model's picks. Here are several college football odds and betting lines for Arizona State vs. Arizona:

  • Arizona State vs. Arizona spread: Arizona -4
  • Arizona State vs. Arizona over/under: 65.5 points
  • Arizona State vs. Arizona money line: Arizona -190, Arizona State +158
  • Arizona State vs. Arizona picks: See picks here

What you need to know about Arizona State

Though it's been a tumultuous and disappointing season for the Sun Devils, including an early season coaching change, Wyoming transfer running back, senior Xazavian Valladay has been a major success in his one year at ASU. Valladay has rushed for 1,095 yards and 14 touchdowns on 191 attempts and has caught 34 passes for 272 yards and two scores. He should be a strong contender for all-conference honors after the season. The quarterback status for Friday's game is unclear after Trenton Bourguet's disappointing performances the last two weeks. On the season, Bourguet and Emory Jones have combined for 2,637 yards, 15 touchdown passes, and eight interceptions. 

For ASU to hoist the nation's oldest college football trophy, the Territorial Cup, for the sixth straight time, their offense needs to be successful against a Wildcats unit that ranks sixth worst nationally, giving up an average of nearly 462 yards per game. Arizona State's defense is surrendering 416.2 yards per game and 30.8 points per contest so in all likelihood, a high-scoring game is in the cards with perfect weather scheduled in Tucson on Friday.

What you need to know about Arizona

The Wildcats close out an improved 2022 campaign where they have jumped their win total from one in 2021 to at least four in 2022. Unfortunately the season won't be complete without a win over Arizona State for the first time in more than half a decade. Despite a poor effort in last week's 31-20 loss to Washington State, the Wildcats rank 20th nationally in offensive yards per game (460.8) and are averaging 30.2 points per game in 2022. That's a dramatic increase from their 2021 numbers, where the Wildcats averaged just over 357 yards per game and 17.2 points.

Quarterback Jayden de Laura has been a success in his first season in Tucson after transferring from Washington State, having thrown for 3,485 yards with 25 touchdowns and 12 interceptions. He's also added four scores on the ground. For Arizona to be successful against the Sun Devils, it's highly likely that the passing game will have to be firing on all cylinders. Wide receivers Dorian Singer (63-1014-6) and Jacob Cowing (80-1001-7) should merit all-conference honors and freshman Tetairoa McMillan (39-702-8) is likely to make national all-freshman teams. 

How to make Arizona vs. Arizona State picks

The model has simulated Arizona vs. Arizona State 10,000 times and the results are in. The model is leaning Under on the point total, and it also says one side of the spread has all the value. You can only see the pick at SportsLine.

So who wins the Arizona State vs. Arizona matchup? And which side of the spread has all the value? Visit SportsLine now to see which side of the Arizona vs. Arizona State spread to jump on, all from the advanced model that finished the past six-plus years up almost $3,000 on its FBS college football picks, and find out.