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The No. 2 Tennessee Volunteers and the Florida Gators are set to square off in an SEC showdown at 7 p.m. ET on Wednesday at the Stephen C. O'Connell Center. Florida is 12-9 overall and 7-3 at home, while the Volunteers are 18-3 overall and 4-1 on the road. Tennessee has dominated this rivalry of late, winning eight of the last 10 head-to-head matchups and covering the spread in seven of those 10 meetings.

The Volunteers are favored by 5.5 points in the latest Florida vs. Tennessee odds from Caesars Sportsbook and the over/under is set at 132.5. Before entering any Tennessee vs. Florida picks, you'll want to see the college basketball predictions from the advanced computer model at SportsLine.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. The model enters Week 13 of the season 50-29 on all top-rated college basketball picks, returning more than $1,200 for $100 players. Anybody who has followed it has seen huge returns.

Now, the model has set its sights on Florida vs. Tennessee. You can head to SportsLine to see its picks. Here are several college basketball odds for Florida vs. Tennessee:

  • Florida vs. Tennessee spread: Florida +5.5
  • Florida vs. Tennessee over/under: 132.5 points
  • Florida vs. Tennessee money line: Florida +185, Tennessee -225
  • Florida vs. Tennessee picks: See picks here

What you need to know about Florida

Florida is coming off a 64-50 loss to the Kansas State Wildcats in the SEC vs. Big 12 Challenge on Saturday. Colin Castleton had 13 points, eight rebounds and four blocked shots in the loss but it wasn't enough to overcome the fact that the Gators shot just 31.0% from the floor as a team.

It was the second-worst shooting night of the season for Todd Golden's squad and they'll certainly be hoping for a bounce-back but this is still a very defensively oriented squad. Florida's opponents shoot just 39.7% from the floor on the season and Castleton is one of the nation's best rim protectors. He's averaging 14.9 points, 7.6 rebounds, 3.2 blocks and 2.6 assists per game this season.

What you need to know about Tennessee

Meanwhile, Tennessee strolled past the Texas Longhorns with points to spare this past Saturday, taking the game 82-71. Tennessee can attribute much of its success to forward Olivier Nkamhoua, who had 27 points in addition to eight boards, and guard Zakai Zeigler, who posted a double-double on 22 points and 10 assists.

The Volunteers currently lead the nation in field-goal defense (34.5%), 3-point defense (22.0%) and points allowed per game (54.5). And their incredible scoring balance makes them difficult to defend with six players averaging at least 8.6 points per game on the season.

How to make Tennessee vs. Florida picks

The model has simulated Florida vs. Tennessee 10,000 times and the results are in. We can tell you that the model is leaning Over and it's also generated a point-spread pick that is hitting in well over 50% of simulations. You can only see the pick at SportsLine.

So who wins Tennessee vs. Florida? And which side of the spread hits well over 50% of the time? Visit SportsLine now to see which side of the spread to jump on, all from the advanced model that is 50-29 on its top-rated college basketball picks this season, and find out.